Product Overview
? Acetic Acid – Research-Grade Solvent for Peptide Reconstitution & pH Modulation
Synonyms: Ethanoic Acid, Glacial Acetic Acid (diluted)
CAS Number: 64-19-7
Concentration: 0.6%–1.0% aqueous solution (typical for peptide workflows)
Form: Clear, sterile liquid
Use: For laboratory research only. Not for human or veterinary use.
? Overview
Acetic Acid is a polar protic solvent commonly used in peptide science for reconstituting lyophilized compounds, particularly those with hydrophobic, acidic, or amphipathic properties.
When diluted to 0.6–1.0%, it serves as a mild pH-lowering agent that enhances solubility, disrupts aggregation, and supports conformational stability. Its compatibility with dual-phase solubilization workflows makes it a valuable tool in peptide formulation and analytical chemistry.
⚙️ Functional Role in Research
In laboratory settings, Acetic Acid contributes to peptide preparation through several mechanisms:
• Solubility Enhancement – May reduce hydrophobic interactions and improve dissolution rates
• pH Modulation – Adjusts solution acidity to support solubilization of challenging peptide sequences
• Structural Support – Helps maintain peptide integrity during reconstitution and short-term storage
• Carrier System Integration – Often used in combination with bacteriostatic water for dual-phase protocols
These properties make Acetic Acid a versatile solvent for formulation and analytical workflows in non-human research models.
? Research Context
Acetic Acid is routinely employed in laboratory environments for:
• Reconstitution of hydrophobic or poorly soluble peptides
• Metal-binding peptide workflows (e.g., GHK-Cu, MOTS-c, AHK-Cu)
• pH-sensitive formulations requiring acidic conditions
• Analytical chemistry applications such as HPLC, CE, and mass spectrometry prep
Its role is especially critical during initial solubilization phases, where peptide integrity and reproducibility are essential.
? Packaging & Storage
• Supplied in sterile, sealed vials (typically 3ml or 10ml)
• Store at room temperature, protected from light and moisture
• Use aseptic technique when withdrawing
• Discard within 28 days of opening if sterility is compromised
⚠️ Compliance Notice
This product is intended strictly for laboratory research use. It is not approved for human or veterinary applications and must not be used in food, drugs, or cosmetics. All information is based on published scientific literature and is provided for educational and informational purposes only. Researchers are responsible for ensuring compliance with local laws and institutional guidelines.
