Product Overview
? Cagrilintide – Research-Grade DACRA Peptide for Metabolic Pathway Investigation
Synonyms: AM833, NNC0174-0833
CAS Number: 2768074-01-5
Sequence: C₂₈₄H₄₃₀N₇₈O₈₄
Molecular Weight: ~5,800–6,000 Da (approximate)
Form: Lyophilized powder
Purity: ≥98% (HPLC)
Use: For laboratory research only. Not for human or veterinary use.
? Overview
Cagrilintide is a synthetic peptide analog of human amylin, designed to function as a dual amylin and calcitonin receptor agonist (DACRA). It has been structurally optimized for enhanced receptor binding, metabolic stability, and reduced fibrillogenic potential.
In laboratory settings, Cagrilintide is under investigation for its role in appetite signalling, gastric motility, and hormonal modulation. Its extended half-life supports sustained receptor engagement, making it suitable for long-duration metabolic studies in non-human models.
⚙️ Mechanistic Insights
Preclinical research suggests Cagrilintide may influence multiple pathways:
• Amylin Receptor Activation – Studied for effects on postprandial glucagon modulation, gastric emptying, and satiety signalling
• Calcitonin Receptor Engagement – Explored for its role in appetite regulation and metabolic hormone interaction
• Dual-Receptor Synergy – May support multi-hormonal modulation in energy balance studies
These findings are based on published scientific literature and are not indicative of human outcomes.
? Research Context
Cagrilintide is being evaluated in controlled laboratory environments for its relevance to:
• Appetite signalling and caloric intake modulation
• Glucagon and insulin pathway analysis
• Gastric motility and nutrient absorption models
• Combination studies with GLP-1 analogs in non-human systems
All applications are strictly limited to research use and are not intended for therapeutic, diagnostic, or clinical purposes.
? Packaging & Storage
• Supplied as sterile-filtered lyophilized peptide
• Store at –20°C in a dry, light-protected environment
• Reconstitute under sterile conditions using appropriate laboratory solvents
• Refrigerate reconstituted solution at 2–8°C to preserve bioactivity
Note: Solvent compatibility and formulation protocols are available upon request for qualified research institutions
⚠️ Compliance Notice
This product is intended strictly for laboratory research use. It is not approved for human or veterinary applications and must not be used in food, drugs, or cosmetics. All information is based on published scientific literature and is provided for educational and informational purposes only. Researchers are responsible for ensuring compliance with local laws and institutional guidelines.
