Product Overview
? Epithalon – Research-Grade Tetrapeptide for Cellular & Circadian Investigation
Synonyms: Epitalon, AEDG peptide
CAS Number: 307297-39-8
Sequence: Ala-Glu-Asp-Gly
Molecular Weight: ~390.35 Da
Form: Lyophilized powder
Purity: ≥98% (HPLC)
Use: For laboratory research only. Not for human or veterinary use.
? Overview
Epithalon is a synthetic tetrapeptide derived from the amino acid sequence of epithalamion, a pineal gland extract. It was developed for research into telomerase regulation, genomic stability, and circadian rhythm modulation.
In laboratory settings, Epithalon is being studied for its potential role in cellular aging, oxidative stress response, and neuroendocrine signalling. Its compact structure and non-hormonal profile make it suitable for long-term studies in non-human models.
⚙️ Mechanistic Insights
Preclinical studies suggest Epithalon may influence several biological pathways:
• Telomerase Activation – May support telomere maintenance and replicative lifespan in somatic cells
• Melatonin Modulation – Studied for its impact on pineal gland output and sleep-phase regulation
• Antioxidant Response – Associated with upregulation of enzymes like glutathione peroxidase
• Gene Expression – Explored for its role in aging-related transcriptional activity
• DNA Repair Support – Investigated in stress-response models for chromatin remodelling
These findings are based on published scientific literature and are not indicative of human outcomes.
? Research Context
Epithalon is being evaluated in controlled laboratory environments for its relevance to:
• Telomere biology and cellular senescence
• Circadian rhythm and sleep-phase signalling
• Immune system modelling and thymic activity
• Neuroendocrine aging and oxidative stress
• Cardiovascular and metabolic resilience assays
All applications are strictly limited to research use and are not intended for therapeutic, diagnostic, or clinical purposes.
? Packaging & Storage
• Supplied as sterile lyophilized powder
• Store at –20°C in a dry, light-protected environment
• Reconstitute under sterile conditions using bacteriostatic water or saline
• Avoid acidic solvents during reconstitution
• Refrigerate reconstituted solution at 2–8°C for multi-use stability
Note: Solvent compatibility and formulation protocols are available upon request for qualified research institutions
⚠️ Compliance Notice
This product is intended strictly for laboratory research use. It is not approved for human or veterinary applications and must not be used in food, drugs, or cosmetics. All information is based on published scientific literature and is provided for educational and informational purposes only. Researchers are responsible for ensuring compliance with local laws and institutional guidelines.
