Product Overview
GHK‑Cu – Research‑Grade Copper‑Binding Tripeptide for Regenerative and Cellular Pathway Investigation
Synonyms: Copper Tripeptide‑1; Gly‑His‑Lys‑Copper Complex
CAS Number: 89030‑95‑5
Sequence: Gly‑His‑Lys (complexed with Cu²⁺)
Molecular Weight: Approx. 340.8 Da (GHK) / ~403 Da (GHK‑Cu complex)
Form: Lyophilised powder
Purity: ≥98% (HPLC)
Use: For laboratory research only. Not for human or veterinary use.
Overview
GHK‑Cu is a naturally occurring copper‑binding tripeptide composed of glycine, histidine, and lysine.
In research settings, it is widely used to investigate cellular regeneration, extracellular‑matrix signalling, and metal‑peptide interactions in controlled laboratory models.
Its high affinity for copper ions and well‑characterised biochemical activity make it suitable for in vitro and non‑human in vivo studies examining wound‑healing pathways, tissue remodelling, and oxidative‑stress responses.
Mechanistic Insights
Preclinical research has explored GHK‑Cu in relation to several biological processes:
• Copper‑Dependent Enzymatic Activity – Studied for its role in delivering bioavailable copper to enzymatic systems involved in tissue repair.
• Extracellular‑Matrix Regulation – Investigated for its influence on collagen‑related pathways and matrix‑remodelling mechanisms.
• Cellular Regeneration – Examined for its involvement in fibroblast activity, cellular migration, and tissue‑repair models.
• Oxidative‑Stress Modulation – Evaluated for its interaction with antioxidant pathways and redox‑related signalling.
These findings are based on published scientific literature and do not imply any therapeutic or physiological effects in humans.
Research Context
GHK‑Cu is utilised exclusively within controlled laboratory environments for:
• Studies involving copper‑peptide interactions and metal‑ion signalling
• Investigations into extracellular‑matrix biology and tissue‑repair pathways
• Research on oxidative‑stress responses and cellular regeneration
• Comparative studies with unbound GHK and other copper‑binding peptides
This material is not intended for therapeutic, diagnostic, or clinical use.
Packaging & Storage
• Supplied as a sterile‑filtered, lyophilised peptide
• Store at –20°C, protected from light and moisture
• Reconstitute under sterile laboratory conditions using bacteriostatic water or a suitable research‑grade diluent
• Store reconstituted solutions at 2–8°C and use according to institutional guidelines
Additional solubility and technical documentation are available to qualified research institutions upon request.
Compliance Notice
This product is intended solely for laboratory research purposes.
It is not approved for human or veterinary administration and must not be incorporated into food, cosmetics, pharmaceuticals, or any product intended for biological exposure.
All information provided is for scientific and educational reference only. Researchers are responsible for ensuring compliance with all applicable regulations, institutional policies, and safety standards.
