Product Overview
? Ipamorelin – Research-Grade Pentapeptide for Endocrine Axis Investigation
Synonyms: NNC 26-0161
CAS Number: 170851-70-4
Sequence: Aib-His-D-2-Nal-D-Phe-Lys-NH₂
Molecular Weight: ~711.9 Da
Form: Lyophilized powder
Purity: ≥98% (HPLC)
Use: For laboratory research only. Not for human or veterinary use.
? Overview
Ipamorelin is a synthetic pentapeptide classified as a selective growth hormone secretagogue (GHS). It is under investigation in laboratory settings for its ability to activate the GHS-R1a receptor, initiating endogenous GH release in non-human models.
Unlike earlier GHRPs, Ipamorelin has demonstrated minimal impact on cortisol, prolactin, and ACTH levels, making it a focused tool for endocrine axis research and GH pathway mapping.
⚙️ Mechanistic Insights
Preclinical studies suggest Ipamorelin may influence several biological pathways:
• GHS-R1a Activation – May support GH release via somatotroph stimulation
• Somatostatin Suppression – Studied for its role in bypassing GH inhibition
• Endocrine Selectivity – Reported to avoid activation of the HPA axis in non-human models
Its short half-life (~2 hours) and receptor specificity make it suitable for time-sensitive studies in metabolic and regenerative research.
? Research Context
Ipamorelin is being evaluated in controlled laboratory environments for its relevance to:
• Pituitary axis mapping and GH Pulsatility
• Myocyte adaptation and recovery assays
• Bone density and osteogenic signalling
• Lipid metabolism and body composition studies
• Post-injury tissue modelling and repair
All applications are strictly limited to research use and are not intended for therapeutic, diagnostic, or clinical purposes.
? Packaging & Storage
• Supplied as sterile-filtered lyophilized peptide
• Store at –20°C, protected from light and moisture
• Reconstitute under sterile conditions using bacteriostatic water or appropriate diluent
• Refrigerate reconstituted solution at 2–8°C to preserve bioactivity
Note: Solvent compatibility and formulation protocols are available upon request for qualified research institutions
⚠️ Compliance Notice
This product is intended strictly for laboratory research use. It is not approved for human or veterinary applications and must not be used in food, drugs, or cosmetics. All information is based on published scientific literature and is provided for educational and informational purposes only. Researchers are responsible for ensuring compliance with local laws and institutional guidelines.
