Product Overview
Melanotan 2 – Research‑Grade Cyclic Peptide for Melanocortin‑Receptor and Neuroendocrine Pathway Investigation
Synonyms: MT‑2; Melanotan II; MT2
CAS Number: 121062‑08‑6
Sequence: Ac‑Nle‑c[Asp‑His‑D‑Phe‑Arg‑Trp‑Lys]‑NH₂
Molecular Weight: Approx. 1,024 Da
Form: Lyophilised powder
Purity: ≥98% (HPLC)
Use: For laboratory research only. Not for human or veterinary use.
Overview
Melanotan 2 (MT‑2) is a synthetic cyclic heptapeptide analogue of α‑melanocyte‑stimulating hormone (α‑MSH).
In research environments, it is widely used to investigate melanocortin‑receptor signalling, neuroendocrine pathways, and pigmentation‑related biochemical mechanisms in controlled laboratory models.
Its high receptor affinity and structural stability make it suitable for in vitro and non‑human in vivo studies examining MC1R–MC4R interactions, energy‑balance signalling, and peptide–receptor dynamics.
Mechanistic Insights
Preclinical research has explored Melanotan 2 in relation to several biological processes:
• Melanocortin‑Receptor Activation – Studied for its interaction with MC1R–MC5R receptor subtypes.
• Pigmentation Pathways – Investigated for its influence on melanocyte signalling and melanin‑related biochemical models.
• Neuroendocrine Regulation – Examined for its involvement in hypothalamic pathways associated with energy balance in non‑human systems.
• Cyclic Peptide Stability – Evaluated for its enhanced receptor affinity and resistance to enzymatic degradation.
These findings are based on published scientific literature and do not imply any therapeutic or physiological effects in humans.
Research Context
Melanotan 2 is utilised exclusively within controlled laboratory environments for:
• Studies involving melanocortin‑receptor pharmacology
• Investigations into pigmentation‑related biochemical pathways
• Research on neuroendocrine signalling and energy‑balance models
• Comparative studies with α‑MSH, Melanotan 1, and other melanocortin analogues
This material is not intended for therapeutic, diagnostic, or clinical use.
Packaging & Storage
• Supplied as a sterile‑filtered, lyophilised peptide
• Store at –20°C, protected from light and moisture
• Reconstitute under sterile laboratory conditions using bacteriostatic water or a suitable research‑grade diluent
• Store reconstituted solutions at 2–8°C and use according to institutional guidelines
Additional solubility and technical documentation are available to qualified research institutions upon request.
Compliance Notice
This product is intended solely for laboratory research purposes.
It is not approved for human or veterinary administration and must not be incorporated into food, cosmetics, pharmaceuticals, or any product intended for biological exposure.
All information provided is for scientific and educational reference only. Researchers are responsible for ensuring compliance with all applicable regulations, institutional policies, and safety standards.
