Product Overview
NAD⁺ – Research‑Grade Oxidised Nicotinamide Adenine Dinucleotide for Cellular Metabolism and Redox Pathway Investigation
Synonyms: Nicotinamide adenine dinucleotide (oxidised form); β‑NAD⁺
CAS Number: 53‑84‑9
Chemical Class: Pyridine nucleotide coenzyme
Molecular Formula: C₂₁H₂₇N₇O₁₄P₂
Molecular Weight: Approx. 663.4 Da
Form: Lyophilised powder
Purity: ≥98% (HPLC)
Use: For laboratory research only. Not for human or veterinary use.
Overview
NAD⁺ (oxidised nicotinamide adenine dinucleotide) is a naturally occurring coenzyme central to cellular energy metabolism and redox reactions.
In research settings, NAD⁺ is widely used to investigate mitochondrial function, oxidative–reductive cycling, sirtuin activity, and metabolic regulation in controlled laboratory models.
Its well‑characterised biochemical role makes it suitable for in vitro and non‑human in vivo studies examining energy production, DNA‑repair pathways, and enzymatic cofactor dynamics.
Mechanistic Insights
Preclinical research has explored NAD⁺ in relation to several fundamental biological processes:
• Redox Cycling – Studied for its role in electron transfer within metabolic pathways such as glycolysis, the TCA cycle, and oxidative phosphorylation.
• Sirtuin Activation – Investigated for its involvement as a required cofactor in sirtuin‑mediated deacetylation reactions.
• DNA‑Repair Pathways – Examined for its role as a substrate for PARP enzymes in genomic‑stability models.
• Mitochondrial Function – Evaluated for its influence on ATP production, metabolic flux, and mitochondrial homeostasis.
These findings are based on published scientific literature and do not imply any therapeutic or physiological effects in humans.
Research Context
NAD⁺ is utilised exclusively within controlled laboratory environments for:
• Studies involving cellular metabolism and redox biochemistry
• Investigations into mitochondrial function and energy‑balance pathways
• Research on sirtuin signalling, PARP activity, and DNA‑repair mechanisms
• Comparative studies with NADH, NADP⁺, and related metabolic cofactors
This material is not intended for therapeutic, diagnostic, or clinical use.
Packaging & Storage
• Supplied as a sterile‑filtered, lyophilised powder
• Store at –20°C, protected from light and moisture
• Reconstitute under sterile laboratory conditions using a suitable research‑grade aqueous buffer
• Store reconstituted solutions at 2–8°C and use according to institutional guidelines
Additional solubility and technical documentation are available to qualified research institutions upon request.
Compliance Notice
This product is intended solely for laboratory research purposes.
It is not approved for human or veterinary administration and must not be incorporated into food, cosmetics, pharmaceuticals, or any product intended for biological exposure.
All information provided is for scientific and educational reference only. Researchers are responsible for ensuring compliance with all applicable regulations, institutional policies, and safety standards.
