Product Overview
Selank – Research-Grade Tuftsin-Derived Peptide for Neuroimmune and Anxiolytic Pathway Investigation
Synonyms: [Thr-Lys-Pro-Arg-Pro-Gly-Pro], Tuftsin analog
CAS Number: 129954-34-3
Sequence: Thr-Lys-Pro-Arg-Pro-Gly-Pro
Molecular Weight: ~861.0 Da
Form: Lyophilized powder
Purity: ≥98% (HPLC)
Use: For laboratory research only. Not for human or veterinary use.
Overview
Selank is a synthetic heptapeptide derived from the immunomodulatory tetrapeptide tuftsin, engineered to probe interactions between the central nervous and immune systems. It is under investigation for its potential role in modulating GABAergic signaling, cytokine expression, and stress-adaptive neurochemistry.
Its stable structure and CNS-permeable profile make it suitable for in vitro and non-human models exploring neuroimmune and behavioral regulation.
⚙️ Mechanistic Insights
Preclinical research suggests Selank may influence several neurobiological and immunological mechanisms:
• GABA Modulation – Studied for its interaction with GABA_A receptor subunits and anxiolytic-like effects
• Cytokine Regulation – Explored for its role in balancing pro- and anti-inflammatory cytokine expression
• Monoamine Dynamics – Investigated for potential modulation of serotonin and dopamine turnover
• Stress Resilience – May influence behavioural responses to chronic stress and fatigue
These insights are derived from published scientific literature and are not predictive of human outcomes.
? Research Context
Selank is being evaluated in controlled laboratory settings for its relevance to:
• Neuroimmune signalling and cytokine expression models
• Anxiolytic and behavioral stress paradigms in non-human subjects
• GABAergic receptor binding and neurotransmitter modulation
• Comparative studies with benzodiazepine analogs or neuropeptides
All uses are strictly limited to research applications and are not intended for therapeutic, diagnostic, or clinical deployment.
? Packaging & Storage
• Supplied as sterile-filtered lyophilized peptide
• Store at –20°C, protected from light and moisture
• Reconstitute under sterile conditions using bacteriostatic water or appropriate diluent
• Refrigerate reconstituted solution at 2–8°C to maintain stability
Note: Solubility data and formulation guidance available upon request for qualified research institutions.
⚠️ Compliance Notice
This product is intended exclusively for laboratory research use. It is not approved for human or veterinary applications and must not be used in food, drugs, or cosmetics. All information is based on peer-reviewed scientific literature and provided for educational purposes only. Researchers are responsible for ensuring compliance with applicable laws and institutional protocols.
