Product Overview
Semax – Research‑Grade ACTH(4–10) Analogue for Neurochemical and Cognitive Pathway Investigation
Synonyms: Met‑Glu‑His‑Phe‑Pro‑Gly‑Pro; ACTH(4–10) analogue
CAS Number: 80714‑61‑0
Sequence: Met‑Glu‑His‑Phe‑Pro‑Gly‑Pro
Molecular Weight: Approx. 873.0 Da
Form: Lyophilised powder
Purity: ≥98% (HPLC)
Use: For laboratory research only. Not for human or veterinary use.
Overview
Semax is a synthetic heptapeptide analogue derived from the adrenocorticotropic hormone fragment ACTH(4–10). It is widely used in research exploring neurochemical regulation, cognitive‑related pathways, and stress‑response mechanisms.
Scientific investigations focus on its potential involvement in neurotrophic factor expression, monoaminergic activity, and adaptive responses to environmental or physiological stressors in controlled laboratory models.
Its stability and CNS‑relevant profile make it suitable for in vitro and non‑human in vivo studies examining neuroplasticity, learning, memory, and neuroprotective signalling.
Mechanistic Insights
Preclinical research has examined Semax in relation to several neurobiological processes:
• Neurotrophic Factor Expression – Studied for its potential to influence BDNF and related neurotrophic pathways in experimental models.
• Monoaminergic Modulation – Investigated for effects on dopamine and serotonin turnover in non‑human systems.
• Stress‑Response Regulation – Explored for its involvement in adaptive responses to acute or chronic stress.
• Cognitive‑Associated Pathways – Evaluated for its impact on learning, memory, and synaptic plasticity in laboratory subjects.
These findings are based on published scientific literature and do not imply any therapeutic or physiological effects in humans.
Research Context
Semax is utilised exclusively within controlled laboratory environments for:
• Studies involving neuroplasticity, learning, and memory pathways
• Investigations into neurotrophic factor expression and signalling
• Experimental models of stress adaptation and behavioural regulation
• Comparative research involving ACTH‑derived peptides or neuroactive analogues
This material is not intended for therapeutic, diagnostic, or clinical use.
Packaging & Storage
• Supplied as a sterile‑filtered, lyophilised peptide
• Store at –20°C, protected from light and moisture
• Reconstitute under sterile laboratory conditions using bacteriostatic water or a suitable research‑grade diluent
• Store reconstituted solutions at 2–8°C and use according to institutional guidelines
Additional solubility and technical data are available to qualified research institutions upon request.
Compliance Notice
This product is intended solely for laboratory research purposes.
It is not approved for human or veterinary administration and must not be incorporated into food, cosmetics, pharmaceuticals, or any product intended for biological exposure.
All information provided is for scientific and educational reference only. Researchers are responsible for ensuring compliance with all applicable regulations, institutional policies, and safety standards.
