Product Overview
? Semax – Research-Grade ACTH-Derived Peptide for Neuroregulatory Pathway Investigation
Synonyms: [Met-Glu-His-Phe-Pro-Gly-Pro], ACTH(4–10) analog
CAS Number: 80714-61-0
Sequence: Met-Glu-His-Phe-Pro-Gly-Pro
Molecular Weight: ~888.0 Da
Form: Lyophilized powder
Purity: ≥98% (HPLC)
Use: For laboratory research only. Not for human or veterinary use.
? Overview
Semax is a synthetic heptapeptide derived from adrenocorticotropic hormone (ACTH 4–10), designed to modulate neurotrophic and neuroprotective pathways. It is under investigation for its role in brain-derived neurotrophic factor (BDNF) regulation, synaptic plasticity, and oxidative stress resilience.
Its short, stable structure and CNS-targeted activity make it suitable for in vitro and non-human neurobiology models.
⚙️ Mechanistic Insights
Preclinical studies suggest Semax may influence several neurobiological mechanisms:
• BDNF Modulation – Studied for its role in upregulating neurotrophic signaling
• Cognitive Pathways – Explored for effects on learning, memory, and attention-related circuits
• Oxidative Stress – Investigated for potential antioxidant and anti-inflammatory properties
• Neurovascular Support – May influence cerebral blood flow and metabolic resilience
These findings are based on published scientific literature and are not indicative of human outcomes.
? Research Context
Semax is being evaluated in controlled laboratory environments for its relevance to:
• Neurotrophic factor expression and synaptic plasticity
• CNS oxidative stress and neuroinflammation models
• Post-ischemic recovery and neurovascular modulation
• Combinatorial studies with stress-inducing agents or cognitive assays
All applications are strictly limited to research use and are not intended for therapeutic, diagnostic, or clinical purposes.
? Packaging & Storage
• Supplied as sterile-filtered lyophilized peptide
• Store at –20°C, protected from light and moisture
• Reconstitute under sterile conditions using bacteriostatic water or suitable diluent
• Refrigerate reconstituted solution at 2–8°C to preserve integrity
Note: Solvent compatibility and formulation protocols are available upon request for qualified research institutions.
⚠️ Compliance Notice
This product is intended strictly for laboratory research use. It is not approved for human or veterinary applications and must not be used in food, drugs, or cosmetics. All information is based on published scientific literature and is provided for educational and informational purposes only. Researchers are responsible for ensuring compliance with local laws and institutional guidelines.
