Product Overview
SS‑31 – Research‑Grade Mitochondria‑Targeting Tetrapeptide for Oxidative‑Stress and Bioenergetic Pathway Investigation
Synonyms: Elamipretide; Bendavia; MTP‑131
CAS Number: 827022‑33‑3
Sequence: D‑Arg‑Dmt‑Lys‑Phe‑NH₂ (Dmt = 2',6'‑dimethyl‑L‑tyrosine)
Molecular Weight: Approx. 639.8 Da
Form: Lyophilised powder
Purity: ≥98% (HPLC)
Use: For laboratory research only. Not for human or veterinary use.
Overview
SS‑31 (Elamipretide) is a synthetic mitochondria‑targeting tetrapeptide designed to investigate mitochondrial function, oxidative‑stress pathways, and bioenergetic regulation.
In research settings, SS‑31 is widely used to study cardiolipin interactions, mitochondrial membrane stability, and cellular‑energy dynamics in controlled laboratory models.
Its unique aromatic–cationic structure allows selective localisation to the inner mitochondrial membrane, making it suitable for in vitro and non‑human in vivo studies examining mitochondrial resilience and redox‑related signalling.
Mechanistic Insights
Preclinical research has explored SS‑31 in relation to several biological processes:
• Cardiolipin Binding – Studied for its high affinity for cardiolipin, a key phospholipid in mitochondrial membranes.
• Mitochondrial Membrane Stabilisation – Investigated for its influence on membrane potential and structural integrity.
• Oxidative‑Stress Modulation – Examined for its involvement in reducing reactive‑oxygen‑species‑linked pathways in non‑human models.
• Bioenergetic Regulation – Evaluated for its effects on ATP‑production efficiency and mitochondrial electron‑transport dynamics.
These findings are based on published scientific literature and do not imply any therapeutic or physiological effects in humans.
Research Context
SS‑31 is utilised exclusively within controlled laboratory environments for:
• Studies involving mitochondrial function and bioenergetic pathways
• Investigations into oxidative‑stress responses and redox signalling
• Research on cardiolipin interactions and mitochondrial‑membrane biology
• Comparative studies with other mitochondria‑targeting peptides
This material is not intended for therapeutic, diagnostic, or clinical use.
Packaging & Storage
• Supplied as a sterile‑filtered, lyophilised peptide
• Store at –20°C, protected from light and moisture
• Reconstitute under sterile laboratory conditions using bacteriostatic water or a suitable research‑grade diluent
• Store reconstituted solutions at 2–8°C and use according to institutional guidelines
Additional solubility and technical documentation are available to qualified research institutions upon request.
Compliance Notice
This product is intended solely for laboratory research purposes.
It is not approved for human or veterinary administration and must not be incorporated into food, cosmetics, pharmaceuticals, or any product intended for biological exposure.
All information provided is for scientific and educational reference only. Researchers are responsible for ensuring compliance with all applicable regulations, institutional policies, and safety standards.
