Product Overview
? Tesamorelin – Research-Grade GHRH Analog for Endocrine Axis Investigation
Synonyms: Egrifta, TH9507, Tesamorelin Acetate
CAS Number: 218949-48-5
Sequence: C₂₂₁H₃₆₆N₇₂O₆₁S
Molecular Weight: ~5135 Da
Form: Lyophilized powder
Purity: ≥98% (HPLC)
Use: For laboratory research only. Not for human or veterinary use.
? Overview
Tesamorelin is a synthetic 44-amino acid peptide analog of growth hormone-releasing hormone (GHRH), designed for enhanced stability and receptor affinity. It is under investigation in laboratory settings for its ability to stimulate endogenous growth hormone (GH) release via activation of GHRH receptors in the anterior pituitary.
Unlike exogenous GH administration, Tesamorelin preserves physiological feedback loops, making it suitable for studies focused on endocrine rhythm, metabolic regulation, and age-related GH decline.
⚙️ Mechanistic Insights
Preclinical studies suggest Tesamorelin may influence several biological pathways:
• GHRH Receptor Activation – May support pulsatile GH secretion from somatotroph cells
• IGF-1 Elevation – Studied for its role in anabolic and lipolytic signalling
• Feedback Preservation – Maintains hypothalamic-pituitary axis integrity, reducing risk of GH desensitization
• Metabolic Modulation – Explored for its impact on visceral adiposity and lipid metabolism
These findings are based on published scientific literature and are not indicative of human outcomes.
? Research Context
Tesamorelin is being evaluated in controlled laboratory environments for its relevance to:
• Visceral fat distribution and lipodystrophy modelling
• Neuroendocrine signalling and cognitive function
• Peripheral nerve regeneration and tissue adaptation
• Age-related GH decline and metabolic dysfunction
All applications are strictly limited to research use and are not intended for therapeutic, diagnostic, or clinical purposes.
? Packaging & Storage
• Supplied as sterile lyophilized powder
• Store at –20°C in a dry, light-protected environment
• Reconstitute under sterile conditions using bacteriostatic water or saline
• Avoid acidic solvents during reconstitution
• Refrigerate reconstituted solution at 2–8°C to preserve integrity
Note: Solvent compatibility and formulation protocols are available upon request for qualified research institutions
⚠️ Compliance Notice
This product is intended strictly for laboratory research use. It is not approved for human or veterinary applications and must not be used in food, drugs, or cosmetics. All information is based on published scientific literature and is provided for educational and informational purposes only. Researchers are responsible for ensuring compliance with local laws and institutional guidelines.
