Product Overview
VIP – Research‑Grade Neuropeptide for Vasodilation, Immune, and Neuroendocrine Pathway Investigation
Synonyms: Vasoactive Intestinal Peptide; VIP Peptide
CAS Number: 16960‑16‑0
Sequence: His‑Ser‑Asp‑Ala‑Val‑Phe‑Thr‑Asp‑Asn‑Tyr‑Thr‑Arg‑Leu‑Arg‑Lys‑Gln‑Met‑Ala‑Val‑Lys‑Lys‑Tyr‑Leu‑Asn‑Ser‑Val‑Leu‑Thr‑NH₂
Molecular Weight: Approx. 3,326 Da
Form: Lyophilised powder
Purity: ≥98% (HPLC)
Use: For laboratory research only. Not for human or veterinary use.
Overview
Vasoactive Intestinal Peptide (VIP) is a 28‑amino‑acid neuropeptide widely distributed throughout the central and peripheral nervous systems.
In research settings, VIP is used to investigate vasodilation, immune modulation, smooth‑muscle relaxation, and neuroendocrine signalling in controlled laboratory models.
Its broad receptor activity at VPAC1 and VPAC2 makes it suitable for in vitro and non‑human in vivo studies examining inflammatory pathways, autonomic regulation, and peptide–receptor interactions.
Mechanistic Insights
Preclinical research has explored VIP in relation to several biological processes:
• Vasodilation and Smooth‑Muscle Relaxation – Studied for its potent effects on vascular tone and airway smooth muscle.
• Immune Modulation – Investigated for its influence on cytokine signalling and anti‑inflammatory pathways.
• Neuroendocrine Signalling – Examined for its role in autonomic regulation and hypothalamic–pituitary communication.
• Receptor‑Specific Activity – Evaluated for its interactions with VPAC1/VPAC2 receptors and downstream cAMP‑linked pathways.
These findings are based on published scientific literature and do not imply any therapeutic or physiological effects in humans.
Research Context
VIP is utilised exclusively within controlled laboratory environments for:
• Studies involving vasodilation and vascular‑tone regulation
• Investigations into immune‑modulatory and anti‑inflammatory pathways
• Research on neuroendocrine signalling and autonomic regulation
• Comparative studies with PACAP and other neuropeptides
This material is not intended for therapeutic, diagnostic, or clinical use.
Packaging & Storage
• Supplied as a sterile‑filtered, lyophilised peptide
• Store at –20°C, protected from light and moisture
• Reconstitute under sterile laboratory conditions using bacteriostatic water or a suitable research‑grade diluent
• Store reconstituted solutions at 2–8°C and use according to institutional guidelines
Additional solubility and technical documentation are available to qualified research institutions upon request.
Compliance Notice
This product is intended solely for laboratory research purposes.
It is not approved for human or veterinary administration and must not be incorporated into food, cosmetics, pharmaceuticals, or any product intended for biological exposure.
All information provided is for scientific and educational reference only. Researchers are responsible for ensuring compliance with all applicable regulations, institutional policies, and safety standards.
